报告人：阎锡蕴 院士 中国科学院生物物理研究所研究员

报告时间：11月30日11:00

报告地点：特种功能材料重点实验室二楼报告厅

主办单位：特种功能材料重点实验室

欢迎光临！

报告摘要：Nanozyme is a new nanomaterial that possess intrinsic enzyme-like activity, which is another way to create new catalyst. Nanozyme can catalyze enzyme substrates at a mild condition and be used as natural enzyme for medical applications such as detection of infectious diseases, tumor diagnosis and catalytic therapy. Since the first evidence was published a decade ago, the new concept of nanozyme has been widely accepted, with more than 500 kinds of nanomaterials possessing intrinsic enzyme-like activity discovered up to now. These studies have changed the view that inorganic nanomaterials are chemically inert in the biological system. This has directly led to a new concept that nanomaterials could be bioactive, opening a new direction in research, which exploits nanomaterial’s own biological properties rather than combining nanomaterial with other biomaterials, and paving the way for a wide range of applications using nanozyme as enzyme mimics for improving human health and living environment. Here, I would like to introduce the progress of nanozyme and its latest applications in medicine.

阎锡蕴，中国科学院院士，中国科学院生物物理研究所研究员，博士生导师，生物大分子国家重点实验室副主任，中国生物物理学会秘书长。1993年获德国海德堡大学医学博士学位，2015年当选中国科学院院士。系统研究了具有重要临床应用前景的肿瘤新靶点，实现了成果转化。在国际上提出了纳米酶新概念，第一次从酶学角度揭示了无机纳米材料的酶促反应动力学、催化机制，并将其用于污水治理、肿瘤诊断和埃博拉等病毒的检测，部分发明专利已进入美国、欧洲和日本。这项工作不仅揭示了纳米材料新特性、拓展其应用，还为模拟酶的基础和应用研究提供了新思想和新材料。原始论文2007年发表后被他引750余次，其结果被国际同行验证并形成了纳米酶研究与应用的新领域。获国家自然科学奖二等奖。